Cancer Treatment Integration Center in Navamindradhiraj–Kaknanang Buildings at King Chulalongkorn Memorial Hospital, under the Thai Red Cross Society, transforms existing facilities to support cancer treatment and research in line with enhanced safety standards. The design integrates advanced medical technology with energy-efficient strategies, utilizing natural light, sustainable materials, and green spaces to strengthen patients’ well-being. Focused on addressing limited space and long waiting times, the project improves functionality while applying Universal Design principles to ensure accessibility, safety, and comfort for all users.